DEPARTMENT OF ORGANIC AND PHARMACEUTICAL CHEMISTRY

2024-06-05 10:51:09

1. General information

1.1. Introduction of the Department 

The Department of Organic and Pharmaceutical Chemistry is one of the main departments of the Pharmacy Program, specialized in Pharmaceutical Science – School of Medicine, Vietnam National University of Ho Chi Minh City. The Department provides students with basic and specialized knowledge related to structure, physicochemical properties of drugs, drug design, drug discovery and development methodology, as well as drug synthesis.

Name

– Vietnamese: Bộ môn Hóa hữu cơ – Hóa dược

– English: Department of Organic and Pharmaceutical Chemistry

Contact information

– Email: bmhh@medvnu.edu.vn

– Address: Administrative building YA1, Hai Thuong Lan Ong street, VNU-HCM Campus, Dong Hoa ward, Di An city, Binh Duong province; Laboratory: lab 503, building C22, University of Science, VNU-HCM Campus.

Overview

– The Department of Organic and Pharmaceutical Chemistry was established according to the Decision number 248/QĐ-KY of the Dean of the School of Medicine, dated December 5, 2017 on the organizational affairs.

– Currently, the Department is comprised of 06 lecturers; 01 assistant lecturer and 01 technician.

Fields of teaching and research

Teaching

The Department undertakes basic courses of Chemistry (Inorganic Chemistry, Organic Chemistry) and specialized courses for Pharmacy students majoring in Pharmaceutical Science. Our courses provide knowledge about the relationship between structure – pharmacological effects, structure – methods of quality control, formulation, use and storage of drugs; knowledge of drug design, drug discovery and development methodology, as well as drug synthesis. In addition, practical courses also help students practice necessary laboratory skills in the field of Pharmaceutical Science.

Scientific research

– Computer-aided drug design, in silico screening of biologically active structures;

– Isolation and structure determination of natural compounds with biological activity;

– Synthesis of biologically active compounds, semi-synthesis of new compounds derived from natural products;

– Synthesis of peptides, proteins, glycoproteins. Structural analysis and kinetics calculation of folding processes of proteins and glycoproteins;

– Synthesis and establishment of impurity reference standards used in pharmaceutical quality control;

– Studies and synthesis of active pharmaceutical ingredients using new methods, or improving existing synthetic procedures.

Head and Deputy head of the Department:

– Head of the Department from December 2017 to July 2023: Assoc. Prof. Dr. Ngoc Vinh Nguyen

– Deputy head of the Department from September 2023: Dr. Minh Hien Nguyen

1.2. Roles and Responsibilities

– Teaching: 

The Department is in charge of or participates in teaching various courses in the Pharmacy Program, including: Inorganic Chemistry, Organic Chemistry, Medicinal Chemistry 1, Medicinal Chemistry 2, Pharmacology 1, Pharmacology 2, Synthesis of Essential Drugs, New Drug Research and Development.

The Department is in charge of or participates in teaching Chemistry and Pharmacology courses in other Programs, including Medicine, Dentistry, Traditional Medicine and Nursing.

– Scientific research: 

Organization and collaboration in scientific research projects within the School of Medicine or with other Schools and Universities in various fields, including: pharmaceutical chemistry, chemistry of natural products, drug design, formulation, investigation of biological activity, etc… The Department also undertakes the training of students in scientific research, Bachelor’s or Master’s graduation theses supervision. 

1.3. Staff

No.Full namePositionAcademic title, degreeResearch fields
1Minh Hien NguyenDepartment’s Deputy Head PhDResearch on biological activity of natural compounds.Isolation and structural evaluation of biologically active compounds.Synthesis of peptides, proteins, glycoproteins. Structural analysis and kinetics calculation of folding processes of proteins and glycoproteins.
2Kim Anh NguyenLecturerPhD, Pharm.Synthesis of biologically active compounds, semi-synthesis of compounds from materials isolated from biomass.
3Linh TranLecturerPhDComputer-aided drug design and molecular dynamics simulation.
4Huynh Nguyen Khanh TranLecturerPhDIsolation and structural analysis of natural compounds originating from medicinal plants, bacteria and marine invertebrates.
5Toan Quyen PhamLecturerMSc, Pharm.Computer-aided drug design; Preparation and quality control of drugs; Synthesis and application of porous materials in the biomedical field.
6Linh Ty HuynhLecturerMSc, Pharm.Studies and synthesis of active pharmaceutical ingredients using new methods or improving existing methods; Drug formulation, research on pharmaceutical equivalence and quality control of drugs.
7Dang Linh Nguyen TranAssistant lecturerPharm.
8Anh Quan NguyenTechnician

1.4. Scientific research (from 2019)

List of research papers in domestic journals

  1. Lê Minh Trí, Châu Ngọc Trọng Nghĩa, Nguyễn Thị Yến Nhi, Huỳnh Thị Kim Ngân, Nguyễn Minh Hiền. Khảo sát hoạt tính chống oxy hoá, khả năng kháng tế bào ung thư HepG2 in vitro, hàm lượng flavonoid và hợp chất phenol toàn phần của cao methanol bốn loài thực vật tại vùng Bảy Núi, An Giang. Sci. Tech. Dev. J. – Health Sci.; 1(2):86-93, 2020.
  2. Nguyễn Minh Hiền, Phạm Tấn Thi, Huỳnh Thị Kim Ngân, Nguyễn Thị Yến Nhi, Nguyễn Thị Dung, Lê Minh Trí. Khảo sát hàm lượng một số kim loại trong đất bằng phương pháp XRF và đánh giá ảnh hưởng của chúng đến hàm lượng phenolic và flavonoid toàn phần của cao chiết methanol từ hai loài thực vật ở tỉnh An Giang. Sci. Tech. Dev. J.; 4(2):900-909, 2021.
  3. Hien Minh Nguyen, Tran Thi Huong, Do Binh Minh, Ha Thi Loan, Tri Minh Le. Application of response surface methodology to optimize the ultrasound-assisted flavonoid-rich extraction of fish mint (Houttuynia cordata Thunb.). Sci. Tech. Dev. J.; 24(3):1-10, 2021. 
  4. Nguyễn Minh Hiền, Lê Văn Huân, Trần Phương Khánh, Nguyễn Thị Lan, Ngô Đức Phúc, Nguyễn Du Thiện, Bùi Thị Phường, Trần Xuân Diễm, Trần Thị Thanh Ngân, Phan Nguyễn Trường Thắng, Trần Việt Hùng, Lê Minh Trí, Nguyễn Ngọc Vinh. Sử dụng tác nhân khử hoá natri dithionit ứng dụng tổng hợp propacetamol hydroclorid từ phenol. Sci. Tech. Dev. J. – Health Sci; 2(2):147-154, 2021.
  5. Giang Thi Kim Lien, Nguyen Thi Bao Anh, Le Nguyen Thien Han, Le Tu Manh Huy, Le Thi Ngoc Tam,Nguyen Tran Phuoc Thuan, Nguyen Minh Hien. Omicron: Flighty factor challenging global vaccine campaigns or the ending signal of the COVID-19 pandemic. Sci.Tech.Dev.J.; 25(2):2390-2401, 2022.
  6. Duong Trinh Hoang, Nam Tran Hai, Phuong Mai Ha, Hien Nguyen Minh, Thang Phan Truong Viet, Hung Tran Viet. The establishmentof Chemical Reference Substances for Molnupiravir and Favipiravir. Sci. Tech. Dev. J. – Health Sci.; 3(1):393-402, 2022.
  7. Giang Linh Thi Nguyen, Vi Ha, Thanh Van Le, Tri Minh Le, Hien Minh Nguyen, Thao Thanh Vu. “Evaluating in vitro antimicrobial activity of hand sanitizers.” VNUHCM Journal of Engineering and Technology; 5(4):1695-1702, 2022.
  8. Hien Minh Nguyen, Tri Minh Le, Minh Binh Do, Manh Huy Tu Le, Phuoc Thuan Tran Nguyen. Evaluating some factors affecting the loading process of quercitin and rutin into the niosome by ethanol injection method. VNUHCM Journal of Engineering and Technology; 6(1), 1798-1808, 2023.
  9. Hien Minh Nguyen, Han Nguyen Thien Le, Nhi Thi Yen Nguyen, Hoa Thanh Vo, Thi Tan Phan, Chia-Hung Yen. Screening for in vitro inhibiting Nrf2 of some Vietnamese medicinal plants. VNUHCM Journal of Engineering and Technology; 6(3), 1975-1999, 2024.
  10. TP Huynh, L Tran, QH Nguyen, TC Bui, S Ghozy, S Morsy, TM Tieu, NT Huy, HTQ Vu. Complete genome sequences and phylogenetic analysis of dengue virus in Southern Vietnam during 2014-2015. MedPharmRes; 6(3), 2022.
  11. Le Chi Cong, Linh Tran, Le Thi Phong Lan, Giang Jan Nguyen, Mohamed Essam Elrggal, Nguyen Hai Nam, Nguyen Tien Huy, Nguyen Duc Truong Transplant Tourism: A Narrative Review on Progression, Ethical and Legal Issues. MedPharmRes; 7(1):27-38, 2023.
  12. Truong Tan Trung, Tan Khanh Nguyen, Nguyen Phuong Dong, Le Thi Thu Thuy, Cao Van Du, Linh Tran. Investigation of ZINC85862539_679 to inhibit SARS-CoV-2 main protease: DFT calculation and molecular docking. Vietnam Journal of Chemistry; 61(4):412-420, 2023.
  13. Phạm Toàn Quyền, Đỗ Hoàng Hân, Nguyễn Nhân Hậu, Nguyễn Văn Hà, Nguyễn Thị Bảo Anh, Bùi Thị Phường, Huỳnh Linh Tý, Lê Minh Trí. Xây dựng quy trình định lượng đồng thời dextromethorphan hydrobromid và promethazin hydroclorid trong chế phẩm uống bằng phương pháp HPLC”. Tạp chí Y Dược học; 15:41-47, 2021.

List of research papers in international journals

  1. Rajni Kant, Chung-Kuang Lu, Hien Minh Nguyen, Hui-Hua Hsiao, Chao-Ju Chen, Hui-Pin Hsiao, Kai-Jay Lin, Cheng-Chieh Fang, and Chia-Hung Yen. 1,2,3,4,6 penta-O-galloyl-β-D-glucose ameliorates high-fat diet-induced nonalcoholic fatty liver disease and maintains the expression of genes involved in lipid homeostasis in mice. Biomedicine and  Pharmacotherapy; 129:110348, 2020.
  2. Nguyen, Hien Minh, Nhi Yen Thi Nguyen, Nghia Trong Ngoc Chau, Anh Bao Thi Nguyen, Van Kieu Thi Tran, Viet Hoang, Tri Minh Le, Hui-Chun Wang, and Chia-Hung Yen. Bioassay-Guided Discovery of Potential Partial Extracts with Cytotoxic Effects on Liver Cancer Cells from Vietnamese Medicinal Herbs. Processes; 9(11):1956, 2021.
  3. Pham, Thi Tan, Thang Van Le, Khai Van Tran, Diem Xuan Tran, Nghia Ngoc Trong Chau, Ngan Thi Kim Tran, Tri Minh Le, Vinh Ngoc Nguyen, and Hien Minh Nguyen. Synthesis of Ag/GO nanocomposite with promising photocatalytic ability for reduction reaction of p-nitrophenol. Materials Research Express; 8(10):105009, 2021.
  4. Linh Tran, Dao Ngoc Hien Tam, Nguyen Minh Hien, Nguyen Tien Huy. Evaluation of COVID-19 protease and HIV inhibitors interactions. Acta Pharmaceutica; 72(1):1-8, 2022. 
  5. Hien Minh Nguyen, Tam Thi Ngoc Le, An Thanh Nguyen, Han Nguyen Thien Le, Thi Tan Pham. Biomedical materials for wound dressing: recent advances and applications. RSC Advances; 13(8):5509-5528, 2023.
  6. Thi Tan Pham, Toan Cong Le, Minh Hien Nguyen, Thi Ngoc Tam Le, Van-Tung Tra, Xuan-Thanh Bui. Inactivating Escherichia coli using hexagonal array of narrow bandwidth of violet-blue light emitting diode. Case Studies in Chemical and Environmental Engineering; 8:100389-100395, 2023.
  7. Hien Minh Nguyen, Thi Yen Nhi Nguyen, Nguyen Kieu My Vo, Cong Toan Le, Xuan Thanh Bui, Thi Tan Pham. Blue light-emitting diode as the promising photodynamic method for the inactivation of Staphylococcus aureus. Systems Microbiology and Biomanufacturing; 4: 223–229, 2024. 
  8. Minh Hien Nguyen, Dieu Ly Ha, Binh Minh Do, Ngoc Trong Nghia Chau, Thi Huong Tran, Nguyen Thien Han Le and Minh Tri Le. RP-HPLC-Based Flavonoid Profiling Accompanied with Multivariate Analysis: An Efficient Approach for Quality Assessment of Houttuynia cordata Thunb Leaves and Their Commercial Products. Molecules; 28:6378-6393, 2023.
  9. Hien Minh Nguyen, Ngan Thi Kim Huynh, Loan Thi Ha, and Thi Tan Pham. Utilizing X-ray fluorescence (XRF) method to evaluate the content of metal elements in soil and their effects on the total phenolic and flavonoid contents of some medicinal plants. Environmental Monitoring and Assessment; 195:963, 2023
  10. Minh Hien Nguyen, Lan Thi Nguyen, Thien Han Nguyen Le, Trong Nghia Ngoc Chau, Yen Nhi Thi Nguyen, Tan Dat Ha, Phuoc Thuan Tran Nguyen, Thien Bao Chu, Chi Hieu Tran, Minh Tri Le. Response surface methodology for aqueous two-phase system extraction: An unprecedented approach for the specific flavonoid-rich extraction of Houttuynia cordata Thunb. leaves towards acne treatment. Heliyon; 10(4), E25245, 2024.
  11. Mai Thanh Phong, Thanh An Nguyen, Nhi Nguyen Thi Yen, Van Khai Tran, Vinh-Dat Vuong, Minh Hien Nguyen, Tan Thi Pham, Thang Van Le. Evaluation of green-synthesized of silver nanoparticle-loaded graphene oxide (AgNPs@GO) nanocomposite toward biological wastewater filtration. Case Studies in Chemical and Environmental Engineering; In press, 100765, 2024.
  12. Eymery MC, Nguyen KA, Basu S, Hausmann J, Tran-Nguyen VK, Seidel HP, Gutierrez L, Boumendjel A, McCarthy AA. Discovery of potent chromone-based autotaxin inhibitors inspired by cannabinoids. European Journal of Medicinal Chemistry; 263:115944, 2024.
  13. Nguyen KA, Lesur E, Ribéraud M, Sallustrau A, Audisio D, Taran F. Sydnone-Cyanines as Clickable Probes for Fluorescent Labelling. Helvetica Chimica Acta; e202200187, 2023.
  14. Nguyen KA, Conilh L, Falson P, Dumontet C, Boumendjel A. The first ADC bearing the ferroptosis inducer RSL3 as a payload with conservation of the fragile electrophilic warhead. European Journal of Medicinal Chemistry; 244:114863, 2022.
  15. Chaptal V, Zampieri V, Wiseman B, Orelle C, Martin J, Nguyen KA, Gobet A, Di Cesare M, Magnard S, Javed W, Eid J, Kilburg A, Peuchmaur M, Marcoux J, Monticelli L, Hogbom M, Schoehn G, Jault JM, Boumendjel A, Falson P. Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter. Science Advances; 8(4):eabg9215, 2022.
  16. Boukherrouba E, Larosa C, Nguyen KA, Caburet J, Lunven L, Bonnet H, Fortuné A, Boumendjel A, Boucherle B, Chierici S, Peuchmaur M. Exploring the structure-activity relationship of benzylidene-2,3-dihydro-1H-inden-1-one compared to benzofuran-3(2H)-one derivatives as inhibitors of tau amyloid fibers. European Journal of Medicinal Chemistry; 231:114139, 2022.
  17. L Tran, TLB Nghia, A Hendam, NL Vuong, E Alzalal, AM Sayed, MM Hussain, A Sharma, T Tieu, PG Mathenge, K Hirayama, N Alexander, NT Huy. Frequent inappropriate use of unweighted summary statistics in systematic reviews of pathogen genotypes or genogroups. Journal of Clinical Epidemiology; 119:26-35, 2020. 
  18. S Ghozy, L Tran, S Naveed, TTH Quynh, AH Zayan, A Waqas, AKH Sayed, S Karimzadeh, K Hirayama, NT Huy. Association of breastfeeding status with risk of autism spectrum disorder: A systematic review, dose-response analysis and meta-analysis. Asian Journal of Psychiatry; 48:101916, 2020.
  19. DNH Tam, EM Mostafa, VL Tu, AI Rashidy, E Matenoglou, M Kassem, DT Soa, A Bayumi, HES Emam, L Tran, TV Dat, NT Huy. Efficacy of chalcone and xanthine derivatives on lipase inhibition: A systematic review. Chemical Biology & Drug Design; 95(2):205-214, 2020.
  20. S Ghozy, NM Dung, ME Morra, S Morsy, GG Elsayed, L Tran, AS Abbas. Efficacy of kinesio taping in treatment of shoulder pain and disability: a systematic review and meta-analysis of randomised controlled trials. Physiotherapy; 107:176-188, 2020
  21. A Mohammed, DNH Tam, TLH Vu, TM Tieu, MK Elfaituri, NN Trinh, EA Sagheir, L Tran, TTH Loc, SK Low, S Mizukami, K Hirayama, NT Huy. Morinda morindoides: A systematic review of its therapeutic activities. South African Journal of Botany; 131:93-103, 2020.
  22. TT Tran, F Pan, L Tran, C Roland, C Sagui. The F19W mutation reduces the binding affinity of the transmembrane Aβ 11–40 trimer to the membrane bilayer. RSC Advances; 11(5):2664-2676, 2021.
  23. DNH Tam, NH Nam, MT Elhady, L Tran, OG Hassan, M Sadik, PTM Tien, GA Elshafei, NT Huy. Effects of Mulberry on The Central Nervous System: A Literature Review. Current Neuropharmacology; 19(2):193-219, 2021.
  24. L Tran, I Radwan, SK Low, MR Hashan, MD Gomaa, M Abdelmongy, AI Abdelaziz, A Mohamed, GM Tawfik, S Mizukami, K Hirayama, NT Huy. Role of Th2 and Th17 cells-mediators in pathogenesis of dengue infection: a systematic review and meta-analysis. Acta Tropica; 216:105823, 2021.
  25. DNH Tam, AT Qarawi, MN Luu, M Turnage, L Tran, GM Tawfik, NT Huy. Favipiravir and its potentials in COVID-19 pandemic: An update. Asian Pacific Journal of Tropical Medicine; 14(10):433-439, 2021.
  26. L Tran, AM Makram, OM Makram, MK Elfaituri, S Morsy, S Ghozy, AH Zayan, NH Nam, MMM Zaki, EL Allison, TH Hieu, LL Quang, DT Hung, NT Huy. Efficacy of Kinesio Taping Compared to Other Treatment Modalities in Musculoskeletal Disorders: A Systematic Review and Meta-Analysis. Research in Sports Medicine; 31(4):416-439, 2023.
  27. L Tran, DNH Tam, A Elshafay, T Dang, K Hirayama, NT Huy. Quality assessment tools used in systematic reviews of in vitro studies: A systematic review. BMC Medical Research Methodology; 21(1):1-13, 2021.
  28. L Tran, DNH Tam, H Elhadad, NM Hien, NT Huy. Evaluation of COVID-19 protease and HIV inhibitors interactions. Acta Pharmaceutica; 72(1):1-8, 2022.
  29. L Tran, DNH Tam, A Reda, AH Tahoon, JMA Aziz, PTM Tien, NH Nam, KM Shahin, J Shah, S Mizukami, NT Huy, K Hirayama. A systematic review of antimalarial activities of Morinda species. South African Journal of Botany; 148:396-406, 2022.
  30. L Tran, NM Tuan, DNH Tam, A Alshareef, E Emad, AM Khalifa, TH Hieu, Z AliKhan, LW Jun, K Hirayama, NT Huy. The timing setting in kinetic dengue studies: a systematic review. Acta Tropica; 234:106584, 2022.
  31. NPH Tao, D Nguyen, SM Sediqi, L Tran, NT Huy. Healthcare collapse in Afghanistan due to political crises, natural catastrophes, and dearth of international aid post-COVID. Journal of Global Health; 13:03003, 2023
  32. Tam DNH, Nam NH, Cuong, NTK, DT Hung, DT Soa, A Altom, L Tran, H Elhadad, NT Huy. Compound K: A systematic review of its anticancer properties and probable mechanisms. Fundamental & Clinical Pharmacology; 37(4):684-712, 2023. 
  33. L Tran, VL Tu, MN Dadam, JMA Aziz, TLD Duy, HHH Ahmed, PA Kwaah, HN Quoc, TV Dat, S Mizuta, K Hirayama, NT Huy. Antimalarial activities of benzothiazole analogues: a systematic review. Fundamental & Clinical Pharmacology; 38(3):410-464, 2024.
  34. M Alied, A Salam, SM Sediqi, PA Kwaah, L Tran, NT Huy. Disaster after disaster: the outbreak of infectious diseases in Pakistan in the wake of 2022 floods. Annals of Medicine and Surgery; 86(2):891-898, 2023.
  35. Hung, D.T., Tran, L., Tam, D.N.H. et al. The prevalence of Pfk13 polymorphism in malaria patients treated with artemisinin-based therapy: a systematic review and meta-analysis. Parasitol Res; 123(5):209, 2024. 
  36. Hoang, T.C., Nguyen, M.T., Nguyen, T.Q., Ho, B.T.Q., Nguyen, H.T., Ngo, T.P.D., Tran, H.N.K. and Bui, T.K.L., 2024. In vitro anti-leukemia, antioxidant, and anti-inflammatory properties of Lantana camara. Brazilian Journal of Biology, 84, p.e279899
  37. Huynh Nguyen Khanh Tran, Min Jin Kim, A-Young Shin, Le Viet Ha Tran, Jihoon Lee, and Yeon-Ju Lee. Coscinoderines A–J: Trisubstituted Pyridinium-Containing Norterpenoids Isolated from Coscinoderma bakusi, a Tropical Marine Sponge. Journal of Natural Products; 86(9):2145-2150, 2023.
  38. Huynh Nguyen Khanh Tran, Min Jin Kim, and Yeon-Ju Lee. Scalarane Sesterterpenoids Isolated from the Marine Sponge Hyrtios erectus and their Cytotoxicity. Marine Drugs; 20(10):604, 2022.
  39. Ha, Manh Tuan, Phuong Thao Tran, Huynh Nguyen Khanh Tran, Okwha Kim, Jeong Ah Kim, Jeong-Hyung Lee, and Byung Sun Min. Anti-osteoclastogenic effects of indole alkaloids isolated from barley (Hordeum vulgare Var. Hexastichon) grass. Journal of Agricultural and Food Chemistry; 69(44):12994-13005, 2021.
  40. Li, Huan, Joonki Kim, Huynh Nguyen Khanh Tran, Chang Hwan Lee, Jonghyun Hur, Min Cheol Kim, and Hyun Ok Yang. Extract of Polygala tenuifolia, Angelica tenuissima, and Dimocarpus longan reduces behavioral defect and enhances autophagy in experimental models of Parkinson’s disease. NeuroMolecular Medicine; 23:428-443, 2021.
  41. Huynh Nguyen Khanh Tran, Ui Joung Youn, Jeong Ah Kim, Hyunsik Chae, Sanghee Kim, and Byung Sun Min. Glycerols and fatty acids isolated from Micractinium sp. KSF0031. Biochemical Systematics and Ecology; 89:104000, 2020.
  42. Huynh Nguyen Khanh Tran, Kang-Hyun Han, Yong-Bum Kim, Mi Hee Woo, Jeong Ah Kim, and Byung Sun Min. Analysis and stability test of the water extract and powder from Polygoni Multiflori Radix for toxicity study. Korean Journal of Pharmacognosy; 51(1):86-91, 2020.
  43. Huynh Nguyen Khanh Tran, Ui Joung Youn, Minji Kim, Thao Quyen Cao, Jeong Ah Kim, Mi Hee Woo, Sanghee Kim, and Byung Sun Min. Biological Activity of Chemical Constituents Isolated from Strain Chlamydomonas sp. KSF108 (Chlamydomonadaceae). Natural Products Sciences; 26(1):59-63, 2020.
  44. Huynh Nguyen Khanh Tran, Thao Quyen Cao, Jeong Ah Kim, Mi Hee Woo, and Byung Sun Min. Anti-inflammatory and cytotoxic activities of constituents isolated from the fruits of Ziziphus jujuba var. inermis Rehder. Fitoterapia; 137:104261, 2019.
  45. Huynh Nguyen Khanh Tran, Jeong Ah Kim, Ui Joung Youn, Sanghee Kim, Mi Hee Woo, and Byung Sun Min. Investigation of chemical compounds from Chlamydomonas sp. KSF108 (Chlamydomonadaceae). Biochemical Systematics and Ecology; 83:4-6, 2019.
  46. Tran, Phi-Long, Okwha Kim, Huynh Nguyen Khanh Tran, Manh Hung Tran, Byung-Sun Min, Cheol Hwangbo, and Jeong-Hyung Lee. “Protective effects of extract of Cleistocalyx operculatus flower buds and its isolated major constituent against LPS-induced endotoxic shock by activating the Nrf2/HO-1 pathway.” Food and Chemical Toxicology; 129:125-137, 2019.
  47. Tran, Phuong Thao, Thi Quynh-Mai Ngo, Suhyun Lee, Okwha Kim, Huynh Nguyen Khanh Tran, Cheol Hwangbo, Byung Sun Min, and Jeong-Hyung Lee. Identification of anti-osteoclastogenic compounds from Cleistocalyx operculatus flower buds and their effects on RANKL-induced osteoclastogenesis. Journal of Functional Foods; 60:103388, 2019.

List of domestic conference papers

  1. Do Binh Minh, Nguyen Du Thien, Le Nguyen Thien Han, Le Thi Ngoc Tam, Nguyen Quang Duc, Nguyen Thi Bao Anh, Nguyen Minh Hien; Impact of COVID-19 vaccination on mertality rate – lessons from the world; Hội thảo Khoa học Trẻ “Vaccine COVID-19: Nghiên cứu và Ứng dụng”, Hà Nội, 2021.
  2. Hien Minh Nguyen, Nguyen Thien Han Le, Tran Phuoc Thuan Nguyen, Binh Minh Do, Ngoc Trong Nghia Chau, Tan Thi Pham and Minh Tri Le. Utilizing response surface methodology for optimizing quercetin loaded niosome by ethanol injection method. The 4th International Workshop on Advanced Materials and Devices 2023, Thai Nguyen, Vietnam. 2023. [Oral].
  3. Nguyen Thien Han Le, Tran Phuoc Thuan Nguyen, Binh Minh Do, Ngoc Trong Nghia Chau, Tan Thi Pham, Minh Tri Le, and Hien Minh Nguyen. Preparation of Houttuynia cordata extract loaded niosome formulation by ethanol injection method. The 4th International Workshop on Advanced Materials and Devices 2023, Thai Nguyen, Vietnam. 2023. [Poster]. 
  4. Khanh Tran Phuong Nguyen, Nhi Thi Yen Nguyen, Nguyen Thien Han Le, Thi Ngoc Tam Le, Hoa Thanh Vo, Thanh Huu Nguyen, Minh Hien Nguyen, Ly Dieu Ha. DNA Barcoding for species discrimination in Luvunga scandens, Triphasia trifolia and Trigonostemon reidioides. The 4th International Conference of School of Medicine, Ho Chi Minh, Vietnam. 2023. [Poster]  
  5. Nhu Quynh Ngoc Huynh, Thien Han Nguyen Le, Anh Tuyet Thi Le, Hai Duong Le, Minh Hien Nguyen, Dieu Ly Ha. Integrating chromatographic fingerprinting and multivariate analysis for quality assessment of Houttuynia cordata Thunb. leaves and powdered products. The 4th International Conference of School of Medicine, Ho Chi Minh, Vietnam. 2023. [Poster]  
  6. Tam Thi Ngoc Le, Nhi Thi Yen Nguyen, Anh Thi Bao Nguyen, Vu Thanh Nguyen, Chia Hung Yen, Hien Minh Nguyen. Investigating the inhibition of Nrf2 expression of Vietnamese medicinal plants on Huh7 cancer cells and Zebrafish model. The 4th International Conference of School of Medicine, Ho Chi Minh, Vietnam. 2023. [Poster]  
  7. Nguyen Thi Lan, Chau Ngoc Trong Nghia, Nguyen Tran Phuoc Thuan, Nguyen Minh Hien, Le Minh Tri. Response surface methodology for aqueous twophase system extraction: an unprecedented approach for the specific flavonoid-rich extraction of Houttuynia cordata Thunb. leaves towards acne treatment. The 4th International Conference of School of Medicine, Ho Chi Minh, Vietnam. 2023. [Poster]

List of international conference papers

  1. Nguyen Minh Hien. Bioassay Accompanied Machine Learning as an Efficient Approach for Identifying Natural Compounds Towards Regulating Nrf2 for Cancer Treatment. The 16th Asian Congress on Biotechnology 2023, Ho Chi Minh, Vietnam. 2023. [Invited Speaker]. 
  2. Nguyễn Minh Hiền. Quy hoạch vùng trồng dược liệu đặc hữu kết hợp ứng phó biến đổi khí hậu tại các tỉnh Tây Nam Bộ. Hội thảo Sâm và Hương liệu, dược liệu quốc tế Thành phố Hồ Chí Minh. Hồ Chí Minh, Việt Nam. 2024. [Invited Speaker]

List of scientific research projects at all levels that have been accepted

  1. Đề tài “Nghiên cứu hoạt tính gây độc tế bào ung thư gan của các phân đoạn cao chiết từ một số cây thuốc nam” mã số C2019-44-02 do TS. Nguyễn Minh Hiền chủ nhiệm, đạt loại Tốt.

STAFF

PhD. Nguyen Minh Hien

LLKH

PhD. Pharm. Nguyen Kim Anh

LLKH

PhD. Tran Thi Thuy Linh

LLKH

PhD. Tran Huynh Nguyen Khanh

LLKH

MSc. Pharm. Pham Toan Quyen

LLKH

MSc. Pharm. Huynh Linh Ty

LLKH

Pharm. Nguyen Tran Dang Linh

LLKH

Technician Nguyen Anh Quan (updating)